PersoMed-I is phase II, randomised international trial of personalised therapy, including sonidegib, for adolescents and young adults with SHH pathway activated medulloblastoma.
Study Chair
Co-Chairs: Professor David Ziegler and Associate Professor Liz Hovey
Multi-centre, international, randomized, open-label Phase II trial
Cancer Type
Medulloblastoma
Intervention
Sonidegib and radiotherapy
Publications
DEVELOPMENT OF RANDOMIZED TRIALS IN ADULTS WITH MEDULLOBLASTOMA—THE EXAMPLE OF EORTC 1634-BTG/NOA-23.
Peter Hau, Didier Frappaz, Elizabeth Hovey, Martin G. McCabe, Kristian W. Pajtler, Benedikt Wiestler, Clemens Seidel, Stephanie E. Combs, Linda Dirven, Martin Klein, Antoinette Anazodo, Elke Hattingen, Silvia Hofer, Stefan M. Pfister, Claus Zimmer, Rolf-Dieter Kortmann, Marie-Pierre Sunyach, Ronan Tanguy, Rachel Effeney, Andreas von Deimling, Felix Sahm, Stefan Rutkowski, Anna S. Berghoff, Enrico Franceschi, Estela Pineda, Dagmar Beier, Ellen Peeters, Thierry Gorlia, Maureen Vanlancker, Jacoline E. C. Bromberg, Julien Gautier, David S. Ziegler, Matthias Preusser, Wolfgang Wick and Michael Weller. Development of Randomized Trials in Adults with Medulloblastoma—The Example of EORTC 1634-BTG/NOA-23.
Cancers. 13(14), 3451 (2021).
Published online 9 July 2021. Article available on https://doi.org/10.3390/cancers13143451